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Experienced and professional animal trainer provide their insights in answering this question :
A. Don’t apply any meds without consulting the specialist. Otoscopic exam is necessary to check what is going on with the ear. If there is a demage of eardrum many drugs given into the ear can lead to hear loss.

How to Identify Common Pet Problems ?

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Antibiotics (e.g., amoxicillin-clavulanate, enrofloxacin, clindamycin, or cefpodoxime) will be used for a bacterial infection for a minimum of six to eight weeks. If the infection is fungal, an anti-fungal medication (most often itraconazole) will be prescribed.
Tacrolimus ointment applied to the external auditory canal is being used in the treatment of chronic non-infectious external otitis refractory to other therapy.
Although it is well known that fungal infection is associated not only with systemic but also with topical steroid therapy, deep dermatophytosis has not been reported during topical tacrolimus therapy. It should be kept in mind that deep fungal infection can be induced by topical tacrolimus ointment.
Some type of maintenance otic therapy is usually required, such as a cleaning and drying agent (to keep the ear canal free of wax buildup), antimicrobial ear cleaners (eg, for recurrent ear infections), and sometimes topical glucocorticoids (for severe hyperplasia or stenosis, when surgery is not an option).
Chronic ear infections in dogs can be caused by a variety of reasons, the most common being allergies. However, they can also be caused by foreign material such as grass or dirt, parasitic causes such as ear mites, ear canal masses and polyps.
Tacrolimus had an antifungal effect against approximately 50% of the Malassezia strains, with MICs ranging from 16 to 32 μg/ml. This agent did not have an antifungal effect against the remaining 50% of the strains.
Use tacrolimus ointment only when you have symptoms of eczema. Stop using tacrolimus ointment when your symptoms go away or when your doctor tells you that you should stop. Do not use tacrolimus ointment continuously for a long time.
Does tacrolimus interact with any foods or beverages? Avoid excessive intake of high potassium foods (bananas, oranges, orange juice, potatoes, spinach, etc). Do not eat grapefruits, grapefruit juice or any soda (Fresca) or fruit juice blend that contains grapefruit juice.
Tacrolimus ointment (0.1%) is safe and effective for long-term treatment of atopic dermatitis in children.
Dogs that have long-standing ear infections may develop an irreversible disease of the ear canal. Due to chronic inflammation, the ear canal becomes very thickened and can turn into bone. As a result, the infection will not resolve with medications.
Left untreated ear infections in dogs can develop quickly and result in symptoms such as balance and coordination issues, pain and in severe cases facial paralysis.
When some dogs eat ingredients such as chicken, wheat, corn or other individual items, ingestion will trigger an allergic reaction that can alter the natural flora and allow an unnatural growth of yeast. If your pet suffers from yeasty ears, attempt altering their diet to eliminate common triggers.
Food allergies are caused by an abnormal immunologic response to a harmless ingested protein. In dogs, food allergies most often cause itchy skin and ears. This can lead to secondary infections of the skin and ears.
The provider may prescribe antibiotics if the infection is caused by bacteria. These medicines may need to be taken for a long time. They can be given by mouth or into a vein (intravenously). If there is a hole in the eardrum, antibiotic ear drops are used.
Zymox: Great At-Home Treatment for Ear Infections in Dogs. Zymox is made for acute and chronic inflammation of the external ear caused by bacterial, viral, and yeast infections. It contains antibacterial, anti-fungal, and antiviral agents.
Tacrolimus should be used on the skin for short treatment periods only. If needed, treatment may be repeated with breaks in between. Use the smallest amount that will treat your condition properly, and apply only on the affected skin. Also, this medication should not be used by children younger than 2 years.
Adults and teenagers 16 years of age and older—Apply 0.03% or 0.1% ointment to a clean, dry, and intact skin two times a day. Children 2 to 15 years old—Apply 0.03% ointment to a clean, dry, and intact skin two times a day. Children younger than 2 years of age—Use is not recommended.
Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal. If you are not sure whether you should start taking this medicine, talk to your doctor.
Are there any potential side effects? Side effects are uncommon but may include mild irritation upon application, eyelid twitches, or hair loss around the eye. Serious side effects include difficulty breathing, facial swelling, hives, weakness, or tiredness.
Usually tacrolimus is taken twice a day, 12 hours apart, such as at 8 a.m. and 8 p.m. Occasionally it is taken only once a day (usually in the morning and at the same time each day) or as often as three times a day (8 hours apart, such as at 7 a.m., 3 p.m., and 11 p.m.). Tacrolimus can be taken with or without food.
Topical tacrolimus is used to treat skin diseases that arise from an overactive immune system such as lupus, pemphigus in dogs or cats, pinnal vascular disease, and perianal fistulas. Ophthalmic tacrolimus is available as an eye drop to treat keratoconjunctivitis sicca (KCS), also known as dry eye in dogs and cats.
Tacrolimus toxicity commonly presents as acute renal failure. Close monitoring of serum creatinine, GFR, and urine output is necessary for patients on tacrolimus. Toxicity may also present as the development of adverse effects such as tremors, electrolyte disturbances, headaches, and increased SCr.
Tacrolimus is an immunosuppressant. It works by decreasing your body`s immune system.

Relevant Questions and Answers :

the most relevant questions and answers related to your specific issue

Q. One of my pet’s ears seems very irritated. What I can use to clean it with?
ANSWER : A. Ear Irritation can be caused by a number of things ranging from allergies, ear infections or even mites. Dirty ears can also cause irritation and problems. Knowing the type of problem is best for figuring out how to treat it.

For plain dirty ears that do not have any odor, redness or leakage of discharge/debris, a simple over the counter canine ear cleaner can be used. Gently soak some cotton balls or a washcloth with the cleaner, and then use these to wipe out the flap of the ear and opening to the ear. Do NOT use Q-tips as these can become stuck or lodged in the curve of the ear canal and may cause injury to the ear drum.

If the ear is bright red or itchy without any dirt or debris in it, it may indicate an allergy. Sometimes an allergy medication can help provide relief in this situation. Your vet can give you the correct dosages of an over the counter allergy medication to use, or may recommend one specifically for dogs.

For infections and mites, changes to the ear such as bad smell or lots of debris and discharge, flecks of black or brown debris, or scabs and sores in the ear may be present. In these cases, it is best to have your vet take a sample of the ear debris to test for mites or infection. Your vet can then give you an ointment that is placed and left in the ear between ear cleanings. Most vets will then recommend cleaning the ears twice daily and then leaving in the ointment after for a period of ten days.

Ear mites ARE contagious to other pets, so if your dog does have them, it is best to treat any other pets in the house at the same time to prevent the mites from spreading around continuously.

Q. Can you use Floxin Otic for ear infections on dogs?
ANSWER : A. Floxin Otic is an ear cleaning solution designed for the clearing of ear infections in people. While it may be similar to dog products used for ear infections, it is best to bring it to your vet’s attention first so he or she can compare it to dog-safe products. It may be that it is in the same concentration and can be safely used, or your vet can instead recommend a product that is in the right formulation.

If you are seeing an ear infection in your dog’s ears, your vet can provide you with a dog-safe medication to use. Ear infections are usually treated over a period of ten days and involve cleaning the ear 2x daily and then placing the otic ointment in the ear to stay in place until the next cleaning.

Q. I have two problems with my 16 yrs old dog: he’s constipated and has a ear ache. What can I use to relieve these?
ANSWER : A. Constipation is a common problem in dogs that can be due to a number of things. However it is a good idea to make sure the constipation is not actually diarrhea, as some dogs can strain after a bowel movement, making it look like such. If constipation is present, adding a little pumpkin puree or plain yogurt to the diet can help make digestion easier and make stools easier to pass. However if symptoms do not resolve after a few days, it is best to speak with your vet.

For ear aches, it is best to have your vet examine the ear as many things including allergies, ear infections, mites and more can cause ear problems. If the ear is just dirty, then cleaning the ear gently with cotton balls or a clean washcloth and a dog ear cleaning solution can help. Do not use Q-tips as a dog’s ear has a 90-degree turn in it and placing Q-tips in the ear can cause damage to the canal or inner ear. However if the problem persists or cleaning does not help, it is best to seek care.

Q. My dog has a bad ear infection, his ear is leaking a smelly fluid. Can he take a penicillin to get rid of it?
ANSWER : A. If your dog has an ear infection it is best to have your veterinarian examine it. Ear infections, depending on their type are treated differently. The most common way to treat an ear infection is through daily cleaning of the affected ear and then placement of a medicated ointment that stays in the ear until the next cleaning. Oral antibiotics are sometimes used, but usually in cases where the infection has spread or ointment has not cleared it up.

Do not use penicillin to treat your dog unless instructed by your veterinarian to do so. Penicillin is a general antibiotic and may not be the right choice for treating this particular infection. The wrong dosage can also cause your dog to become very ill.

Q. My dog is having ear problems. I have had her at two vets and they can not seem to find the cause. Can you help?
ANSWER : A. For a pet with chronic ear issues I would recommend checking her thyroid levels. Hypothyroidism can be a cause of chronic ear infections.

Then I would recommend having a bacterial culture of the ear debris to ensure the appropriate antibiotic is chosen to completely rid the bacteria in there. If there is resistant bacteria, the ear will appear to get better at first but then once ear meds are stopped they will thrive again and cause a re-emergency of the ear infection. Also longer treatment may be needed, for example instead of 7-10 days, perhaps 14 days continuously.

If all else fails, I would recommend a skull radiographs to look for signs of a narrow ear canal and/or an inner ear infection which will require not only topical antibiotic ointments put into the ear, but also oral antibiotics.
Most ear infections are caused by moisture in the ears, narrow ear canals, hypothyroidism or skin allergies. Each one has to be gone through systematically.

Q. It seems that my dog has a systemic fungal infection. Are there any home remedies that I can try?
ANSWER : A. Systemic fungal infection is extremely rare and very difficult to diagnose. So, first of all I would challenge any diagnosis of systemic fungal infection made on the base of clinical examination or routine investigation like bloods, ultrasound scan or x-ray. This disease requires long term anti-fungal therapy and all of these drugs are prescription only medications. Systemic fungal infection is usually related to suppressed immune system. It may happen to dogs on immunosupressive therapy ( treatment for tumours or auto-immune diseases), in dogs that have been on long antibiotics therapy or dogs with any serious concurrent diseases.

Q. My Bulldog puppy growls, barks and even tries to bite me when I say “no” to him. What can I do?
ANSWER : A. First, avoid scolding him and acting aggressively towards him if you don’t want him to be acting aggressively towards you. There are other methods you can use to communicate to your dog that you don’t want him to continue doing what he is doing. I recommend you stop telling him “no”, scolding him, or raising your voice at him. Everything coming from you should be 100% positive and 100% calm.

Try to figure out ways to clearly communicate what you want to your dog. If you want your dog to leave something or someone alone, I strongly suggest teaching your dog commands like “leave it”. Here is a link to a video in which I explain how to do it:

www.youtube.com/watch?v=R1TS5nA7z5Q

Another thing I suggest you use is a no-reward marker. This clearly communicates when your dog has done something wrong. No-reward markers have to be introduced during your training sessions. You should be doing at least three training sessions per day, that are something like 3-10 minutes long (working on different things each training session). If you are teaching your dog something BRAND NEW, do not use the no-reward marker, as you do not want to discourage your dog from performing behaviors for you. Use the no-reward marker for known behaviors only. Here is another helpful video about this:

www.youtube.com/watch?v=sdU5a6fXKlg

Lure each new behavior (as shown in the video) using high value treats. Let’s say you’re working on “down” which is a behavior your dog knows fairly well. Present the treat to your dog. Ask your dog to “down” (only ask once). If he does not go “down” immediately, say, “uh-oh” or “eh-eh” in a gentle tone, and then place the treat behind your back. This communicates to your dog that they did something to make the treat go away.

After you place the treat behind your back to show your pup “that was wrong” you need to communicate to your pup “let’s try again” by getting your pup to walk around for a second, and then start the behavior all over again. If your puppy is very young, chances are you haven’t taught him a solid “down” behavior yet. So, as I said, do not use this method until you have lured each new behavior as shown in the video.

This is the order in which you should teach behaviors: Lure using a high value treat as shown in the video. After a few successful food lures, lure with an empty hand. If the pup is successful with the empty hand lure, reward with lots of treats. If the pup is unsuccessful, then go back to food-luring a couple more times. After a few successful empty-hand lures, you can begin to add the cue. Say “sit”, then lure with an empty hand, and then reward. Once your pup understands the cue, begin to work on the no-reward marker.

Q. Can I use tacrolimus in ears. Dog has had systemic fungal infection 2 yrs ago and is now under control. Ear is closed and meds difficult to admin.
ANSWER : A. Don’t apply any meds without consulting the specialist. Otoscopic exam is necessary to check what is going on with the ear. If there is a demage of eardrum many drugs given into the ear can lead to hear loss.