Experienced and professional animal trainer provide their insights in answering this question :
A. I’ve never seen that reaction from frontline before so I would think it is probably something else causing it, maybe a dermatitis. I would recommend having it checked by your vet especially if it is not improving or is bothering her.

How to Identify Common Pet Problems ?

Our sources include academic articles, blog posts, and personal essays from experienced pet care professionals :

Signs of flea control product toxicity can occur from one to 12 hours after application and may vary depending on the type of flea control product poisoning. The most common signs of toxicity from pyrethrum-based flea products are muscle tremors and excessive salivation.
Side Effects of Frontline®

Side effects with any of the topical Frontline® products are uncommon but may include itching, redness, or irritation at the site of application. If any signs of skin irritation occur, bathe your pet with mild soap and large amounts of water.

How long does flea and tick medicine poisoning last? Symptoms may continue for several days after the use of a product, but most clinical signs will resolve in one to three days.
Poisoning as a result of exposure to flea and tick products is one of the most common types of poisoning in dogs. Symptoms of poisoning from flea and tick medication range from drooling, vomiting, and diarrhea, to lack of coordination, weakness, and seizures.
Your cat may experience skin irritation at the application site. If you notice signs of an allergic reaction, such as difficulty breathing or convulsions, contact your vet immediately.
Side effects may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects occur, consult your veterinarian or call 1-800-660-1842, M-F 8am-8pm EST.
Frontline Plus for dogs is generally safe to use and causes few side effects. Mild skin irritation may occur but should clear up quickly. Additional side effects may include vomiting, diarrhea, and seizure. However, these side effects are extremely rare and tend to affect smaller dogs.
Poisoning symptoms in cats usually occur minutes to hours after exposure to or application of the flea and tick medicine, but may be delayed up to 72 hours. The symptoms typically last two to three days. The most common symptoms of flea and tick medicine poisoning in cats include: Tremors/muscle twitching/trembling.
If an animal is able to lick the product when it is wet on the fur or scratches the area and then licks their foot, the bitter taste of the product can cause the animal to salivate, foam at the mouth, become nauseous or vomit. Also, some cats have been known to become agitated and run around the house.
If your pet happens to lick the topical flea medication, give them a small amount of their food to help relieve the bad taste. Next, contact your veterinarian or the APCC for additional steps to take and signs to monitor for.
Advantage flea medication is commonly used to rid cats of fleas and is considered safe. However, some cats develop an allergy to the medication, and if this occurs, it is important to contact your veterinarian.
Symptoms of toxicity can include twitching, hypersalivation, trembling and seizures. If you start to see tremors shortly after applying the flea treatment, the best thing to do is bathe Fluffy or Fido in lukewarm water with a gentle dish soap like Dawn or Palmolive.
FRONTLINE® Plus for Cats kills adult fleas and ticks, prevents new infestations by killing flea eggs and larvae to break the flea lifecycle, and lasts for a full 30 days.
Keep your pet dry for 48 hours.

Your pet should not get wet for 48 hours after you apply Frontline.

It`s important to avoid contact with the medication for at least 24 hours after it has been applied, as it can be risky if you touch the area before it has had time to absorb into your pet`s skin. After that time period has passed, however, you can safely interact with your dog as normal.
The EPA has determined fipronil to be safe for use on dogs and cats, with no harm to humans who handle these animals. Poisoning cases from accidental use or misuse of fipronil may occur in animals.
Change the First Aid Statements to read as follows: If on skin or clothing: -Take off contaminated clothing. –Rinse skin immediately with plenty of water for 15-20 minutes. -Call a poison control center or doctor for treatment advice. If in eyes: -Hold eye open and rinse slowly and gently with water for 15-20 minutes.
So, if you are concerned about ticks on your furry pal then Frontline plus is the best option. While if adult fleas, flea larvae and chewing lice is you concern then you can opt for Advantage.
Flea and tick medicine poisoning occurs when your cat has a negative reaction to the medication. The chemicals from the medication disrupt the nervous system and can lead to serious health problems. It is usually found in topical medication that is applied to the neck and back.
It is not used in humans, but humans might accidentally take an animal`s medication or come into contact with it in the form of an agricultural spray. Minor side effects such as GI upset and drowsiness might occur if that happens. No human overdoses have been published.
FRONTLINE PLUS is water-fast. It is OK to bathe your pet before using FRONTLINE PLUS, but the coat should be completely dry prior to application. In the 48 hours immediately after treatment, do not bath, shampoo or let your dog go swimming. Cats can be bathed from 24 hours after treatment.
Pyrethrin based insecticides, often used in flea and tick treatments for both cats and dogs, can be toxic to your cat if ingested and can cause excessive drooling and foaming at the mouth.
As a result, it`s smart to treat any cat—including an indoor one—with a flea and tick preventive, says Annie Harvilicz, chief medical officer at Animal Wellness Centers, in Los Angeles.

Relevant Questions and Answers :

the most relevant questions and answers related to your specific issue

Q. My cat is excessively scrstching herself., to the point she has sores. She is strictly an indoor cat. Did have flees been treated for 2 months
ANSWER : A. For every flea you see on your pet, there are 100 more in the environment. Get your pet on a good topical or oral flea control through your vet. In flea control, you get what you pay for. Consider asking your vet for a dose of Capstar. It helps get the problem under control by killing the fleas on the pet starting in five minutes but only lasts for 24 hours.

You need to treat your home environment. If you use a pest control service, tell them you are having a flea problem and they can adjust their treatment. Use a premise spray that also contains an IGR, insect growth regulator. This keeps eggs and larvae from maturing into adults and helps break the life cycle. Also, vacuum EVERY DAY, throwing out the bag or emptying the canister every time into an outside receptacle and spraying the contents with insecticide to kill the fleas you’ve vacuumed up.

Treat your yard too, since fleas are opportunistic and will hop a ride into your home on your pant leg without you knowing it. Concentrate on areas under bushes, in the shade. Fleas are less likely to be located in open sunny areas where it gets hot.

If chemicals are a problem, you can use borax. Sprinkle it into rugs, into corners and under furniture, use a broom to work it into the fibers and let it sit for hours, days even. It won’t hurt you or your pet to have it present. Then vacuum it up, reapply as needed. Food grade diatomaceous earth can be gotten from a health food store and worked into the rugs and corners in the same way as borax. These treatments aren’t as fast and effective as chemical insecticides but they can help.

You might want to consider boarding your pet for the day at your vet, to give you the opportunity to flea bomb your house without having to worry about your pet being exposed. They can bathe your pet and give a dose of Capstar while you treat your home.

Be patient, you may have to repeat these steps multiple times 10-14 days apart to help break the flea life cycle.

Skin problems can have a variety of causes, sometimes more than one. It is important to have the problem checked by your vet to determine if there is a medical cause for your pet’s skin issues and treat accordingly.

In pets of all ages, fleas, food allergies and exposure to chemical irritants such as cleaners and soaps can be a cause. Any one of these may not be enough to trigger the breakouts, depending on how sensitive your pet is, but a combination can be enough to start the itch-scratch cycle. Finding out the cause and eliminating it is the best course of action. With flea allergies, if your pet is sensitive enough, a single bite can cause them to break out scratch enough to tear their skin.

Check for fleas with a flea comb. Look for fleas and/or tiny black granules, like coarse black pepper. This is flea feces, consisting of digested, dried blood. You may find tiny white particles, like salt, which are the flea eggs. Applying a good topical monthly flea treatment and aggressively treating your house and yard will help break the flea life cycle.

If you use plastic bowls, this is a possible cause for hair loss, though this tends to be on the chin, where their skin touches the bowl while they eat. If you suspect this to be the culprit, try changing the bowls to glass, metal or ceramic.

Food allergies are often caused by sensitivity to a protein in the food. Hill’s Science Diet offers some non-prescription options for sensitive skin as well as prescription hypoallergenic foods for more severe cases. Royal Canin carries limited protein diets that may also offer some relief. Your vet can recommend a specific diet that will help.

If there is no relief or not enough, consider getting your pet checked by a veterinary dermatologist and having allergy testing done.

Q. Why do cats meow?
ANSWER : A. Cat parents often wish they could better understand what their favorite feline friends want or desire. A cat’s meow can be interpreted in many different ways and can indicate an array of feelings and needs. Here are some of the most common reasons for your cat’s vocalizations:

1. Greeting- Many cats will meow as a greeting when you enter your home or walk into a room. Cats will also meow at another cat or animal in the household to extend a hello and acknowledge the other animal’s presence.

2. Attention – An exuberant meow followed by leg rubbing or another attention seeking behavior may indicate your cat is looking for some quality time spent together. Some petting or rubbing behind the ears may be in order.

3. Hunger – A meowing cat is often a hungry cat. This is one of the most common reasons for a cat to vocalize to their owners. A cat will meow to get your attention at feeding times or even when they want extra food.

4. Sickness – A sick or hurt cat may begin to meow excessively, warranting a visit to the veterinarian. There are numerous reasons for a cat in distress to meow—whether it is related to an upset stomach, an injured leg or a urinary blockage. These meows should be carefully investigated.

5. Entering or leaving – Most cats will vocalize when they want to be let in or out of a room. You may notice when you are in the bathroom or behind the closed door of a room that your cat begins to meow, scratches at the door, and often reaches its paw under the door. This is a clear indication that the cat wants to be where you are.

6. Angry – An agitated cat may meow to warn their owner or another household pet that they are upset and would like to be left alone. This angry meow may increase in sound volume as the cat becomes more stressed or agitated. Often a cat will exhibit this type of meow at the veterinary office when they are unhappy with their examination or restraint.

Each feline is different and so are their vocalizations. Learn to understand the variety of meows your cat uses on a daily basis. This will help you develop a better relationship with your cat and help them live a more trusting and happier life.

Q. My cats nose is stopped up on antibiotics. She has a loss of appetite, acting normal though. Is 3 ounces of can food enough in 24h? 9 pound cat
ANSWER : A. Cats with stopped up noses tend to eat much less, as you’ve noted, because they can’t smell their food as well. And the smell of food is pretty important to a cat’s appetite. You can start by warming up the food in a microwave – not too hot, test it yourself by putting your finger right in the center, as the temperature of microwave food can vary – as this will intensify the smell and hopefully make your cat more interested.

Saline nose drops, like those that are used on little kids, are safe to use on a cat to clean the discharge that is dried around and in the nose. There’s a brand called Little Noses that’s available in the U.S. That I like. You can put it on a q-tip and try to remove the debris. Humidifying the air with a humidifier can help as well, or you can put the cat in the bathroom and run the shower enough to generate steam. Don’t use “real” nose drops like Neo-synephrine or anything else like that – cats quickly build up resistance to them.

A 3 oz can of food is an OK amount in 24 hours, but do try the techniques above to help your cat get more interested in food. You might also try some baby food – no garlic or onions in the ingredients – as cats usually really like the taste of it.

Q. My cat has a major rash on her back it looks like red bumps an some have even turned into scabs.
ANSWER : A. Skin disorders can be particularly vexing to diagnosis and treat. One of the most common causes of skin rashes in cats is allergic dermititis caused by the bites of fleas. Some cats are very sensitive to the bite(s) of fleas and will react with excessive itching, scratching, and scabby bumps particularly on the lower back and nape of neck. Finding fleas on your cat is a pretty good indicator that fleas are causing the skin irritation. Unfortunately, NOT finding fleas doesn’t rule out an allergy to fleas, as it takes only one bite from a flea to cause a reaction in sensitive cats. Moreover, there are many other possible causes for skin rashes in cats, including thyroid disease, fungal diseases, bacterial or viral infections, and irritation from chemicals in the enviroment (scented litter, fabric sheets, air freshners, floor and carpet cleaners, etc.).
A trip to the veterinarian is your first step in treating skin disorders. Your vet will examine your cat, checking for fleas and other external parasites and also looking at the distribution pattern of the rash which will help your vet to determine what might be causing the rash. If necessary, your vet may take hair or skin samples for analysis. Blood work may also be necessary if your vet suspects thyroid diseases or another metabolic disorder.

Q. Frontline is not working on my dog, what should I use?
ANSWER : A. Frontline works best if it is given either three days before or three days after bathing your pet as it is absorbed through the skin. Frontline works on pets, but you will need to continually give treatment for up to three months before the environment and your pet are fully flea-free. Your pet can continue to get fleas from the environment as the eggs hatch and attempt to jump on your pet. Making sure to clean the area your pet is in, such as washing bedding and vacuuming carpeting (especially areas with cracks such as along the wall) can also accelerate flea removal. If your pet still has fleas and you want immediate relief, your vet can provide you with an oral medication such as capstar to kill fleas depending on when the last Frontline dose was given.

Pets can continue to itch for a while even after the fleas themselves are treated. Flea bites can cause an allergy, called flea allergy dermatitis, which can cause itching, scratching and redness on the skin. While many owners think this means fleas are still there, it could just be the skin healing from bites. An allergy medication and preventing your pet from scratching can provide relief during the healing process.

Read Full Q/A … : FAQ

Q. My cat continues to scratch on furniture and carpets. He has plenty of scratching posts around the house. Please help!
ANSWER : A. Scratching is a natural behavior in cats that can be frequently frustrating for pet owners who want to keep their furniture from being shredded on a constant basis. The texture of furniture and carpet is very appealing to cats and this why they frequently choose to spend their time on this activity as opposed to playing with their own cat toys. Here are some suggestions to help curb this unwanted behavior:

1. Purchase a cat scratching post or cat tree that is covered in carpeted or textured material. Place it in an appealing spot that your cat would be inclined to spend time (eg. in the sun). You can also place catnip on the scratching post or cat tree to make your cat even more interested in the new object.

2. You can utilize double sided tape on the ends of the furniture because you cat will not like the sticky feeling and will learn to not scratch in that region. Use the tape that has a lighter adhesive in order to prevent any permanent damage. Other materials, such as aluminum foil or bubble wrap can also be placed on the furniture to discourage the scratching.

3. Keep nails trimmed short by either learning to do this on your own at home or using a veterinary technician, or groomer. Nails can usually be trimmed every 6-8 weeks.

4. Redirect the unwanted behavior. If your cat begins scratching, use a favorite or new toy to distract the cat from the scratching. Give your cat positive praise for not scratching.

5. As a last resort you can use a spray bottle full of water to spritz your cat when he or she is scratching inappropriately at your furniture. Generally, cats do not like water and this will discourage them from continuing the behavior.

Have patience with your cat because it can takes time to understand this is an unwanted behavior and that furniture is not another toy for them to use. You can always consult your veterinary or veterinary behaviorist to help with ideas or further solutions to this problem.

Read Full Q/A … : I found Pickle on

Q. My 13 year old male cat is acting lethargic & doesn’t seem to be feeling well. I don’t know what’s wrong except that he has fleas. Can too many fleas
ANSWER : A. Excessive fleas can cause anemia in cats, left untreated, this can be life-threatening. I recommend getting your cat seen by your vet right away for his illness. For every flea you see on your pet, there are 100 more in the environment. Get your pet on a good topical or oral flea control through your vet. In flea control, you get what you pay for. Consider asking your vet for a dose of Capstar. It helps get the problem under control by killing the fleas on the pet starting in five minutes but only lasts for 24 hours.

You need to treat your home. If you use a pest control service, tell them you are having a flea problem and they can adjust their treatment. Use a premise spray that also contains an IGR, insect growth regulator. This keeps eggs and larvae from maturing into adults and helps break the life cycle. Also, vacuum EVERY DAY, throwing out the bag or emptying the canister every time into an outside receptacle and spraying the contents with insecticide to kill the fleas you’ve vacuumed up.

Treat your yard, since fleas will hop a ride into your home on your pant leg without you knowing it. Concentrate on areas under bushes, in the shade. Fleas are less likely to be located in open sunny areas where it gets hot.

If chemicals are a problem, you can use borax. Sprinkle it into rugs, into corners and under furniture, use a broom to work it into the fibers and let it sit for hours, days even. It won’t hurt you or your pet. Then vacuum it up, reapply as needed. Food grade diatomaceous earth can be gotten from a health food store and worked into the rugs and corners in the same way. These treatments aren’t as fast and effective as chemical insecticides but they can help.

Be patient, you may have to repeat these steps multiple times 10-14 days apart to help break the flea life cycle.

Q. How do I FINALLY rid all 4 of my cats of tapeworms after 2 years of dealing with it? Fleas seem to be controlled. I know they are the vector.
ANSWER : A. If your cats keep getting tapeworms, then they are picking up fleas from somewhere. Fleas will hitch a ride on your pant leg from outside.

Get your pet on a good topical or oral flea control through your vet. In flea control, you get what you pay for. Consider asking your vet for a dose of Capstar. It helps get the problem under control by killing the fleas on the pet starting in five minutes but only lasts for 24 hours.

You need to treat your home environment. If you use a pest control service, tell them you are having a flea problem and they can adjust their treatment. Use a premise spray that also contains an IGR, insect growth regulator. This keeps eggs and larvae from maturing into adults and helps break the life cycle. Also, vacuum EVERY DAY, throwing out the bag or emptying the canister every time into an outside receptacle and spraying the contents with insecticide to kill the fleas you’ve vacuumed up.

Treat your yard too, since fleas are opportunistic and will hop a ride into your home on your pant leg without you knowing it. Concentrate on areas under bushes, in the shade. Fleas are less likely to be located in open sunny areas where it gets hot.

You can also use borax. Sprinkle it into rugs, into corners and under furniture, use a broom to work it into the fibers and let it sit for hours, days even. It won’t hurt you or your pet to have it present. Then vacuum it up, reapply as needed. Food grade diatomaceous earth can be worked into the rugs and corners in the same way as borax. These treatments aren’t as fast and effective as chemical insecticides but they can help.

You might want to consider boarding your pet for the day at your vet, to give you the opportunity to flea bomb your house without having to worry about your pet being exposed. They can bathe your pet and give a dose of Capstar while you treat your home.

Be patient, you may have to repeat these steps multiple times 10-14 days apart to help break the life cycle.