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Experienced and professional animal trainer provide their insights in answering this question :
A. Heat can be connected with suppression of immune system. Symptoms during this time can be connected with some viral or bacterial infection.

How to Identify Common Pet Problems ?

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Pyometra may occur in any sexually intact young to middle-aged dog; however, it is most common in older dogs. Typically, the dog has been in heat within the previous four weeks. After many years of estrus cycles without pregnancy, the uterine wall undergoes the changes that promote this disease.
Dogs with pyometra typically have a white, yellowish, or green discharge from the vagina. They may also be drinking excessively and urinating frequently. If you see any of these indicators, bring your pup to the vet immediately. There are also two types of pyometra, and these include open or closed pyometra.
In an open pyometra the pus discharges out of the vagina – as seen by a yellow, green or red/brown copious discharge from the vulva of the dog. The diagnosis of an open pyometra is therefore easier if there is a visible discharge. A closed pyometra is when the cervix is closed and there is no discharge.
A blood tinged vaginal discharge lasts for seven to ten days and precedes estrus or true heat. The vaginal discharge changes from red to yellowish in color during true heat. At this stage, females are receptive to males and may be successfully bred.
The initial stage of pyometra usually comes with a slight vaginal discharge with no prominent symptoms. Pets diagnosed with pyometra later show visible signs. Dogs with pyometra also have an increased white blood cell count and globulins in the blood. Some dogs may also have painful, enlarged abdomen.
Pyometra can develop at any stage of the estrous cycle, although it is more common 1-2 months after estrus. The signs depend on whether the cervix is open or closed.
Ampicillin/ amoxicillin was an effective first choice antimicrobial in cases requiring antibiotic treatment. Further studies are needed to identify cases benefiting from antibiotic treatment, as well as the duration of treatment needed to reduce the infection rate while also avoiding unnecessary preventive treatment.
Infections that cause yellow vaginal discharge are usually bacterial, so they may be treated with antibiotics. Your doctor can determine the best course of treatment for you, depending on your medical history, symptoms, and diagnosis.
Discharge. A small amount of odorless, clear discharge can be entirely normal for your female dog. If they`re not neutered, you might notice that the amount and type of discharge vary at different times in their cycle too. During their season, you`ll also see some pink or bloody discharge.
Pyometra is a very serious infection of the womb, also known as the uterus. It`s caused by the womb filling with pus and, if left untreated, it can lead to kidney failure, toxaemia, dehydration and, in some cases, death.
Proestrus. This is the start of your dog`s heat cycle. Het hormones are beginning to rise and her body is preparing her for mating. Early signs of the proestrus stage include a swollen vulva and vaginal discharge that will range from being white, pinkish, or reddish in color.
A small amount of yellowish-white or even slightly green-tinged discharge can collect around the opening to a dog`s prepuce. This is called smegma and is normal.
Pyometras are categorized as “open” or “closed.” In an open pyometra, infectious material leaks from the uterus; owners may notice a bloody, yellow, or cream-colored discharge on their dog`s fur near the uterine opening or on their bedding.
However, most dogs with pyometra are not seen until later in the illness. A very ill female dog that is drinking an increased amount of water and has not been sterilised is always suspected of having pyometra. This is especially true if there is a vaginal discharge or painful, enlarged abdomen.
SIGNALMENT. It has been suggested that pyometra is a condition of middle aged and older dogs. 22-25 However, pyometra has been reported in dogs as young as 4 months old and as old as 16 years.
Pyometra most often occurs in the weeks following a heat cycle, as hormonal changes create the opportunity for infection. Pets typically become ill very suddenly and although their clinical signs can be severe, owners don`t know what is wrong.
As mentioned above, early cases of pyometra can often be treated by removing the uterus. Pagan says, “A typical recovery time is 14 days and most dogs do very well after the fact.” If left untreated, the infection can leak into the abdomen.
The treatment for green discharge is usually antibiotics, either taken orally or given as an injection. The first step is for the doctor to identify which STI is causing the green discharge. Once a doctor knows whether it is trichomoniasis, gonorrhoea or chlamydia, they can prescribe you the appropriate treatment.
Historically, aglepristone has been shown to disengage progesterone`s support of pregnancy by blocking its receptors. By taking over the progesterone receptors, the drug also removes the effect progesterone plays in containing pyometra, allowing the dog`s natural uterus purging mechanism to occur.
Prostaglandin F2-alpha is the most commonly used medication to medically manage pyometra in dogs. Prostaglandins induce regression of the corpora lutea (luteolysis) through numerous mechanisms, including constriction of blood vessels responsible for oxygen delivery.
Of all the drugs causing contraction of the uterine musculature (PGF2a, oxytocin, ergot derivatives) PGF2a is the one which is most indicated for the clinical treatment of pyometra.
Yellow discharge may or may not indicate an infection. If the discharge is a pale yellow, odorless, and not accompanied by other symptoms, it may not be a cause for concern. In other instances, yellow discharge can be a sign of a sexually transmitted infection (STI) or a bacterial infection.
Pre-oestrus: The start of pre-oestrus can generally be precisely pinpointed, since it is accompanied by highly visible changes to the female dog in question. Its vulva swells and bloody vaginal discharge is secreted. This phase tends to last nine days, but variations between three and 17 days are not uncommon.

Relevant Questions and Answers :

the most relevant questions and answers related to your specific issue

Q. Our 2 yr old Weimeraner female had greenish yellow discharge before and after her heat cycle. She was given an antibiotic before her cycle and it cle
ANSWER : A. Heat can be connected with suppression of immune system. Symptoms during this time can be connected with some viral or bacterial infection.

Q. Hi my dog breast is swollen what i do
ANSWER : A. If your pet is not spayed or was spayed after 1-2 years of age there is a chance that this swelling could be mammary cancer. Mammary cancer in pets is common and the chances of cancer are decreased an the risk of getting cancer is only 0.5% if spayed before the 1st heat cycle, 8% if spayed before the 2nd heat cycle, 26% if spayed by the 3rd heat cycle. After the 3rd heat cycle spaying a pet will not decreased chances of mammary cancer.
I would highly advise that you take your pet tot he vet to have this area examined. Typically mammary cancer lumps are firm and can be on multiple breasts.
Without seeing the lump myself, another possibility here is a lipoma (soft fatty tumor) or an abscess.

Q. Hi I just bought a German shepherd who is almost 3 months old, h has gotten his 1st puppy shots from his previous owner, what other shots does he need
ANSWER : A. Puppies should be given 3 rounds of vaccinations, ideally at 8, 12, and 16 weeks. Typically the vaccination against distemper and parvo (that’s one vaccination against 2 diseases) is given at all 3 visits. Rabies is given only once when they are 16 weeks old.

Depending on where you live and your puppy’s lifestyle, your vet may also recommend a vaccination against leptosporosis (given at 12 and 16 weeks) and against kennel cough (it varies, but they are usually given two of those as well).

Read Full Q/A … : Aggressive Puppy

Q. 5mnth at most fm kitten has thick yellow vaginal discharge. Stomach seems slightly enlarged/hard.Doesn’t seem ill. Eating playing good.NO VET AVAILBL!
ANSWER : A. This discharge can be connected with proestrus phase of cycle. In a few days you should notice symptoms of heat. If discharge is thick, yellow-white, bad smelling see a vet

Read Full Q/A … : R

Q. We have a 3 yr old Weiner dog, she is having pus in her eyes, I took her to the vet he gave me derma vet ointment, used it as the doctor prescribed
ANSWER : A. If the pus really isn’t all that bad, and it’s just some discharge, your pup may benefit from a diet change. It could be that the food you’re feeding just isn’t right for your dog, and that’s okay! Dogs grow and change over time, and now that your dog is fully matured, a diet change may be in order. Try something like Taste of the Wild, maybe a grain free dog food, Orijen, or Ziwipeak. These are all really great food options.

If the pus is really bad, and continues to get worse, see your vet again and let them know what’s going on. Maybe you could try a diet change, and then see if there are any improvements.

Remember, you should always gradually change a dogs diet. By gradually, I mean you put a tiny bit of new kibble in with a bowl of the old kibble. Reduce the old kibble by just a few bits of kibble. Throughout the course of at least two weeks (or as long as you want depending on whether or not you want to finish off the old food) you slowly add more of the new kibble while removing some of the old kibble. This makes the process gradual, and won’t cause any tummy-upset in your dog.

Q. I have a 13 year old intact female Chihuahua who has a clear/reddish discharge coming from her genital area.She doesn’t act sick. Been over a week.
ANSWER : A. It can be normal discharge connected with the heat. see your vet if it will persist longer than 2 weeks or you will notice other concerning signs like vomiting, lethargy, increase urination and water intake, white or bad -smelling vaginal discharge

Q. What can I do if my pet is suffering mucus nasal discharge?
ANSWER : A. Diseases of the nasal cavity, paranasal sinuses or lower respiratory tract typically cause nasal discharge, sneezing and snorting.

Other common causes of nasal discharge include viral, bacterial or fungal infections, foreign bodies, allergies, polyps, neoplasia, and extension of diseases from oral cavity.

In most of instances dogs will require treatment with antibiotics, anti-inflammatory or antihistamine medications and in cases of persistent nasal discharge further investigation like x-ray of the nasal cavity, endoscopy, culture of the nasal mucus is warranted. Therefore, it is strongly advised to have your pet checked by your veterinarian if the discharge persists.

Q. i believe my cat is pregnant but showing signs of being in heat
ANSWER : A. Cats are induced ovulators, meaning they will continue to go into heat until they are bred, or spayed (reproductive organs removed). If your cat is showing signs of being in heat (excessive yowling, presenting her rear to you for inspection, attempting to get out or other cats hanging near your house) and you don’t want kittens, it is best to have her spayed. Most cats are also semi-seasonal in their heat cycle meaning they will more likely be in heat through Spring-Summer than in Fall-Winter.

Pregnancy in cats lasts about 60 days. Signs of pregnancy may include weight gain, increased appetite, nipples that become pronounced or “leak” and seeking nesting areas to deliver kittens. If you saw that your cat was in heat, or had her mated, you can use the date she was bred to determine when she may be due for kittens. Your local vet can help determine if she is indeed pregnant and can also take an X-ray to determine the number of kittens present if your cat is nearing her due date. Be sure to feed mom a kitten formula in the last few weeks of her pregnancy and during nursing as it will help provide extra beneficial nutrients for both mom and babies.

If you do not want kittens, some very early term pregnancies can be aborted with spaying, otherwise spaying mom is usually done when kittens are weaned from their mom.