Experienced and professional animal trainer provide their insights in answering this question :
A. Depending which country you live in there maybe products that are licensed for guinea pigs (for example Xeno). If there are any licensed meds your vet should be able to administer off licensed medication to your guinea pig.

How to Identify Common Pet Problems ?

Our sources include academic articles, blog posts, and personal essays from experienced pet care professionals :

Human lice treatments are far too strong for a small rodent and pet store treatments can be dangerous in their own right, causing seizures or simply not work. 1 It`s much safer to have your vet use a medication that is dosed appropriately and documented for use in a guinea pig.
Your vet will prescribe a treatment with ivermectin or selamectin. Both of these can treat a mange mite infestation. Your vet will administer ivermectin with an injection, orally or topically. Because injections can be painful for guinea pigs, we recommend topical or oral treatment.
As expected, guinea pigs can experience intense itching from lice infestation, which will inevitably lead to skin irritation and lesions. Your guinea pigs may also experience some weakness due to anemia caused by the blood loss that comes from lice infestation.
Use a guinea pig shampoo, which you can find in most pet stores. If you have multiple pigs, you should bathe them more often. Use anti-mange shampoo. The anti-mange shampoo will help to prevent your pig from getting sarcoptic mites.
Washing, soaking, or drying items at a temperature greater than 130°F can kill both head lice and nits. Dry cleaning also kills head lice and nits. Only items that have been in contact with the head of the infested person in the 48 hours before treatment should be considered for cleaning.
Sometimes, simply combing your child`s hair to remove the lice and nits (eggs) can be effective. While time-consuming, studies show that combing injures the lice, so they rarely survive.
More commonly, domestic guinea pigs live an average of 5 years. In the wild, guinea pigs typically live for 1-4 years, as they are a common prey species and live in sometimes harsh environments. Male guinea pigs are called boars, while female guinea pigs are called sows.
Guinea pigs with mites are usually treated with ivermectin, which can be administered by injection, orally, or topically. This needs to be done in a few doses, usually two or more with a week to a week and a half between each dose.
Unless a medicated shampoo is prescribed by your exotic vet, we recommend holding off on bathing a guinea pig suffering from mites until the little demons are under control and your guinea pig is feeling more comfortable. Mite infestations are generally treated with ivermectin.
Avermectin-containing products and several acaricides/insecticides that can be administered topically provide excellent control of mites. Avermectin products persist in pig tissues long enough to control most mite infections following a single dose.
Self-care. Whether you use nonprescription or prescription shampoo to kill lice, much of the treatment involves self-care steps you can take at home. These include making sure all the nits are removed and that all clothing, bedding, personal items and furniture are free of lice.
In actuality, untreated head lice may degrade the scalp and affect its health. It will also affect your hair`s health as well. If the hair follicles become blocked, then hair loss may occur. It is hard to have well-conditioned hair if it is covered in head lice, lice eggs, and bacteria.
Olive Oil smothers and kills active head lice, making nit removal easier and moisturizing the hair and scalp. Part hair and apply the oil directly onto the scalp. Massage into the entire scalp making sure to saturate the hair. Apply a shower cap.
If the freezer is 5°F or lower, all lice and eggs should be dead within 10 hours. Also, keep items and areas off-limits to people for 48 hours to limit exposure to any live lice.
The two common guinea pig fur mites are Trixacarus caviae (sarcoptic mange mite) and Chirodiscoides caviae. Your guinea pig may acquire these fur mites from other infested guinea pigs that she comes in contact with or from previously contaminated bedding. Mites can affect a guinea pig of any age or sex.
As part of our expanding range of Pet Shampoo`s & Conditioners , this shampoo has been specifically designed for Guinea pigs to help control most common parasites such as Static Lice, Mites, Ticks & Fleas.
You will be able to see the lice in the coat of the guinea pig, usually around the rump or the back of the neck. They are about 1mm long and cream coloured.
Hog lice, like most lice, are host specific. They usually spread among swine when the pigs are in close contact, as when they crowd together for warmth, shade or comfort. Also, lice can spread to pigs moved into quarters recently vacated by lousy animals. Infested animals added to a clean herd often introduce lice.
Although the mites will clear up and hair will start growing back after the second treatment, continue to give a third or fourth treatment to ensure that the mites are gone. One tube will last a long time, so if you have a few other guinea pigs, you may want to treat them as well to prevent the spread of parasites.
Ivermectin can be used topically to kill mange mites and may also kill lice and fur mites. It is safe for pregnant sows and young that have reached 12 ounces (340 grams) in weight. Repeat treatment at least once 7 to 10 days later to kill emerging mites (eggs are not killed). Treat all guinea pigs simultaneously.
Try not to use straw, hay or newspaper: Mites and lice love heat and dampness, so eliminating these from the housing helps to keep the parasites away. Straw and hay also both harbour mites in the stalk tubes and contain dust spores, while newspaper will `wick` wetness and get damp.
Adult Guinea Pig

Please do not use coconut oil. It does not have any medicinal purpose and has no evidence for its use in mite treatment.

Straw itch mites have a stylet-like mouthpart that is used to inject saliva containing a toxin into hosts. The toxin present in the saliva paralyzes their prey and allows them to feed on them. Although the mites cannot successfully use humans as hosts, they will readily bite humans.

Relevant Questions and Answers :

the most relevant questions and answers related to your specific issue

Q. What is the best treatment for guinea pig lice?
ANSWER : A. Depending which country you live in there maybe products that are licensed for guinea pigs (for example Xeno). If there are any licensed meds your vet should be able to administer off licensed medication to your guinea pig.

Q. My guinea pig has diarrhea and is weak and falling over.
ANSWER : A. It sounds like your guinea pig is very sick and needs to be seen by a vet to determine the cause and best treatment. It could be an infection, parasite, metabolic disease ( liver, kidney, etc), or some type of tumor. Please call a vet and have your guinea pig treated.

Q. How can I get rid of fleas on my dogs for good. I tried everything and nothing helps.
ANSWER : A. The best option for you would be to treat your dog, house, and yard. You will need to treat all of those three things. Get your dog on Frontline and Hartgard that is the best topical treatment for dogs. You must use this product for at LEAST four months to get rid of the entire cycle of the flea. If you have an infestation I would recommend staying on it all year round. Next, visit your local pet store and find the best yard and home flea treatment. If you’re trying everything I would try the best products so you’re not wasting your time with the cheaper low quality products. Ask a pet store associate to help you find the best one. You must treat all three things in order to fully get rid of the fleas, so treat ALL your pets (including cats – use Revolution), your yard, and your house.

Q. My guinea pig has a cloudy and goopy eye. There are no local vets to treat him. Any suggestions?
ANSWER : A. I would highly recommend going to the place you purchased the Guinea Pig from and ask for advice. Ask them to verify that there are no veterinarians that see exotics in the area and ask them what they think you should do for the issue. If you can bring in the G-Pig with you and ask for someone at the pet store who knows a lot about G-Pigs. If there is no one in the store who knows about them ask if there will be someone in who knows about them that you can ask questions to and to leave a message with them. If they are of no help try another pet store with the same questions.

Q. What does it mean when my female guinea pig purrs while I pet her?
ANSWER : A. Are you sure it is a she? Male guinea pigs also make this purring noise when they are showing off as males and wooing a female guinea pig. Females can sometimes also make this noise when they are feeling very happy while being petted. So apparently your cavy likes being petted.

Read Full Q/A … : Guinea Pig Sounds

Q. Hello, my name is Sarah and I have a guinea pig named Harley. He squeaks when he goes to the bathroom. Is that a problem?
ANSWER : A. Guinea pigs squeak a lot about everything. If it looks like he is straining to go especially to urinate then have him checked by your vet. Guinea pigs do suffer from urinary crystals.

Read Full Q/A … : Guinea Pigs – Pinterest

Q. Our dogs have fleas 2 weeks after using frontline treatment. Can we do a treatment of a different brand of flea treatment (advantix) 2 weeks early?
ANSWER : A. It will be safer to wait until 4 weeks after Frontline treatment before you apply Advantix. It is not recommended to use 2 or more flea treatment at the same time.

Q. Canine Rituximab finding this treatment for dog with Lymphoma – otherwise healthy
ANSWER : A. This medication is commonly used to treat lymphoma as well as other blood-borne cancers in human patients. However, trials of this medication in canine patients has had mixed to poor results. As cancer treatments are often very specific to the individual and much more advanced than regular veterinary medicine, it is best to speak with your treating veterinarian or ask for a referral to a veterinary oncologist (cancer doctor). They would be able to better address any questions or specifics regarding lymphoma treatments.

If you’re curious to read a bit more about cancer treatment in dogs including the use of Rituximab, this article may be helpful: http://www.petmd.com/blogs/thedailyvet/jintile/2013/oct/new-treatment-for-dog-cancer-lymphoma-30979

Read Full Q/A … : Canine Lymphoma