Experienced and professional animal trainer provide their insights in answering this question :
A. It depends on the temperature in your carv. If it is cold wwe’re you live and the car would’ve been as cold as a fridge then uit should be fine o

How to Identify Common Pet Problems ?

Our sources include academic articles, blog posts, and personal essays from experienced pet care professionals :

Metronidazole tablets, capsules, and oral solution should be stored in a tightly sealed container, protected from light, and at temperatures below 30°C (86°F). Some special liquid formulations should be stored in the refrigerator.
The suspension is oil-based and does not need to be stored in the refrigerator.
Metronidazole benzoate in SyrSpend SF, which was packaged in amber plastic prescription bottles, is stable for at least 1 year when stored protected from light at ambient condition (25°C/60% relative humidity). The shelf life for this product may be extended to 2 years when stored at refrigerated temperature.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom).
Vaccines and antibiotics often need to be refrigerated to prevent alteration of their chemical structures; such alteration can result in less potent or ineffective medications.
Temperature-sensitive drugs lose potency if not refrigerated and should be replaced with a new supply as soon as possible. Anyone having questions about the safety or storage of any medication they are taking should contact their pharmacist.
Refrigeration is often preferred, and can sometimes taste better for pediatric patients when stored in the refrigerator. Unit-dose antibiotic oral syringes are stable at room temperature for at least 72 hours.
How long does metronidazole stay in your system? For most people, metronidazole may still be present in the body up to 40 hours (a little less than 2 days) after your last dose. But for people with liver problems, this time could rise to 6 days.
After the first dose, it takes 1 to 2 hours for your cat`s body to absorb the medication. Your cat`s diarrhea should start to get better in a few days. Make sure your cat finishes the entire course of metronidazole ordered by the vet, even if their diarrhea has totally cleared up.
Capsules and tablets

Depending on the manufacturer, the stock bottles will typically carry an expiration date of two to three years. However, pharmacists commonly make the expiration date on your prescription about one year — as long as that fits into the expiration time on their stock bottle.

Storage and Stability

Store at controlled room temperature 15–25°C (59–77°F).

Room temperature means 77 degrees. Beyond that, deterioration of the drug begins. Storage is also important while waiting for your refrigerator to kick back on. Morgan says a cool, dark, dry place is best because light and moisture deteriorates drugs.
Many antibiotics are heat-sensitive. Store these products in a refrigerator at a temperature between 2°C and 8°C to maintain their potency. Various other products require storage in a cool (below 15°C), but not refrigerated, location.
Use A Cooler Bag

As long as you can insulate them with ice, they will work. Next, ice packs can be added. If it is easier to use a gel ice pack, the Transport Security Administration allows for them as long as they are presented frozen solid during declaration.

Yes, some medication can be impacted by the cold temperatures sweeping the Pine Belt. Kim Rodgers, owner of Rodgers Family Pharmacy in Petal, said in most cases, a tablet or capsule should be okay. But, it`s diabetic patients that need to be extra cautious in the cold snap.
Suspension: stable after reconstitution for up to 14 days if refrigerated, ideally between 2° C and 8° C (36° F and 46° F). Keep tightly closed. Shake well before using. Sealed aqueous suspensions may be stored for at least 1 year in tightly sealed container.
Amoxicillin tablets or capsules should be stored at room temperature between 59℉ and 86℉ in a dry place. The liquid suspension may be stored in the refrigerator, but this is not strictly required, and cats typically accept liquid medication more readily when it is at room temperature.
How should amoxicillin be stored? Tablets of amoxi/clavulanate are sensitive to moisture and should be protected from humidity. The liquid formula should be refrigerated. If amoxicillin/clavulanate is left out of the refrigerator overnight it should still be good; if longer then discard.
Metronidazole Storage Instructions

The oral liquid forms need to be refrigerated and shaken well before being administered to any dog. This is because the liquid the medication has been dissolved in, can in some cases, expire.

Tylosin is safe for long term use and provides a good alternative to metronidazole, another bowel anti-inflammatory/antibiotic that is not as amenable to long term use.
The bottle should say “refrigerate” on it. Liquid Augmentin® is a medication that must be kept in the refrigerator. Some medications, like liquid amoxicillin, don`t need to be refrigerated, but taste better if you refrigerate them.
These include insulins, antibiotic liquids, injections, eye drops and some creams. These medicines must be stored between 2ºC and 8ºC.
With serious swelling, including dental infections, the medicine will start working within a few days but it may take longer before your symptoms start to get better. For some of the infections that metronidazole is used for, you may only begin to notice an improvement after a week.
To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop using this medicine too soon, your infection may return.

Relevant Questions and Answers :

the most relevant questions and answers related to your specific issue

Q. When I have to put my dog in the car she totally flips out. I put her in a crate and try to talk softly to her. Does not work, what can I do?
ANSWER : A. Your dog will need to be desensitized in baby steps in order to acclimate to the car.

First of all, consider if she’s comfortable with the crate outside the car. If not, start there. Feed her meals in the crate, keep it positive.

Next just have her outside near the car going at her pace and treat her with lots of praise and tasty treats just for being near the car. You will eventually work up to luring her in the car and into the crate rather than forcing her. You can achieve this by using pieces of cheese or hotdog, etc. The goal is to use the tastiest, higher value treats she won’t receive any other time.

In baby steps, once she is comfortable in the crate, start closing the door. Do this over several days. After that, turn the car on and keep giving her treats. After doing that during a few days, drive short distances, and so on.

You may need someone to help you keep giving treats. If she is too stressed out, go back a few steps. Also consider rescue remedy, other anxiety treats, and other calming options such as the Thundershirt.

Q. METRONIDAZOLE Susp 100mg was kept in car overnight. It says to keep refrigerated. Is it safe to use now?
ANSWER : A. It depends on the temperature in your carv. If it is cold wwe’re you live and the car would’ve been as cold as a fridge then uit should be fine o

Q. My Bulldog puppy growls, barks and even tries to bite me when I say “no” to him. What can I do?
ANSWER : A. First, avoid scolding him and acting aggressively towards him if you don’t want him to be acting aggressively towards you. There are other methods you can use to communicate to your dog that you don’t want him to continue doing what he is doing. I recommend you stop telling him “no”, scolding him, or raising your voice at him. Everything coming from you should be 100% positive and 100% calm.

Try to figure out ways to clearly communicate what you want to your dog. If you want your dog to leave something or someone alone, I strongly suggest teaching your dog commands like “leave it”. Here is a link to a video in which I explain how to do it:

www.youtube.com/watch?v=R1TS5nA7z5Q

Another thing I suggest you use is a no-reward marker. This clearly communicates when your dog has done something wrong. No-reward markers have to be introduced during your training sessions. You should be doing at least three training sessions per day, that are something like 3-10 minutes long (working on different things each training session). If you are teaching your dog something BRAND NEW, do not use the no-reward marker, as you do not want to discourage your dog from performing behaviors for you. Use the no-reward marker for known behaviors only. Here is another helpful video about this:

www.youtube.com/watch?v=sdU5a6fXKlg

Lure each new behavior (as shown in the video) using high value treats. Let’s say you’re working on “down” which is a behavior your dog knows fairly well. Present the treat to your dog. Ask your dog to “down” (only ask once). If he does not go “down” immediately, say, “uh-oh” or “eh-eh” in a gentle tone, and then place the treat behind your back. This communicates to your dog that they did something to make the treat go away.

After you place the treat behind your back to show your pup “that was wrong” you need to communicate to your pup “let’s try again” by getting your pup to walk around for a second, and then start the behavior all over again. If your puppy is very young, chances are you haven’t taught him a solid “down” behavior yet. So, as I said, do not use this method until you have lured each new behavior as shown in the video.

This is the order in which you should teach behaviors: Lure using a high value treat as shown in the video. After a few successful food lures, lure with an empty hand. If the pup is successful with the empty hand lure, reward with lots of treats. If the pup is unsuccessful, then go back to food-luring a couple more times. After a few successful empty-hand lures, you can begin to add the cue. Say “sit”, then lure with an empty hand, and then reward. Once your pup understands the cue, begin to work on the no-reward marker.

Q. Which flea and tick drops are the best and why?
ANSWER : A. Your question is a good one, and unfortunately the answers are going to differ based on who you ask. Many vets are seeing resistance to Frontline, which has been the go-to product for many of us for many years. It contains the active ingredient Fipronil, which is very safe and typically extremely effective. I use it on my dogs and never see fleas or ticks. However other vets will tell you in their areas, for whatever reason, they are seeing fleas and ticks on dogs and cats on which this product was used.

Another reason opinions differ is that some people like to give an oral product, and some like to put a topical product directly on the skin. That’s a matter of personal preference mostly. Bravecto, as mentioned below, is one of those products. Most people find it safe and effective. It uses a different process that Frontline to kill fleas and ticks.

In general the products you buy over-the-counter are likely going to be less expensive and less effective than what you get from a vet. I think the reason is that the more expensive products contain newer insecticides, and likely less resistance to these products has built up in the flea and tick population but also they are maybe less “proven”, so it’s important for a vet to be involved in the use of the product in order to ensure that there won’t be a negative reaction to using it.

If I lived in an area where there was Lyme disease (in the US that’s the northeast and upper midwest) I’d most definitely add a tick collar to my standard oral or topical flea and tick prevention. AND I’d search both of my dogs everyday for ticks. It’s because nothing you buy will be 100% effective, and Lyme disease can be a very serious problem.

If you want to talk further and talk more specifically about where you live and what products you’re considering, I’d be happy to do a consult with you. Nobody here is paid to recommend products, but we do develop preferences based on what we use on our own pets and in our practices.

Q. I have a pregnant cat and in a couple of weeks my house is getting sprayed to get rid of fleas. But can I put a flea collar on her?
ANSWER : A. It is best NOT to place a flea collar on a pregnant cat as they can cause problems such as deformities or breathing issues to the unborn kittens. If your cat has fleas you may want to check with your vet to see if there is a pregnancy-safe flea product that can be applied, or you may want to use a safe soap such as Dawn to bathe your cat and then use a fine-toothed comb to brush out the dead fleas. Dawn dish soap is very safe on the body and is often used on kittens that are too young for flea medication to suffocate and kill fleas on the body. Cleaning the environment is also a great way to get rid of the fleas, however be sure to keep your cat away from the area that is sprayed if chemicals are used to prevent injury to her or her unborn kittens.

Q. Are cottonelle moist wipes (designed for humans) safe to use on puppy’s fur?
ANSWER : A. While ingredients of this product are not easy to find, it seems that if the product is safe to use on humans for wiping, it should be OK for use externally to clean off dirt or debris on the fur.

It is best to try a small area of skin to try the product on first, and then watch for any reactions. Signs of adverse reaction include itching, redness, rash or irritation at the site used. If any irritation is seen, use should be discontinued. If no irritation is seen, it should be OK to use the wipes on a larger part of the body.

Q. What’s the best way to ride with my puppy in the car?
ANSWER : A. Your puppy -and dog- should ride in the backseat of the car at all times. To further ensure the safety of your puppy, place him in a crate that has been anchored to prevent it from toppling or being thrown from the car in case of accident, use a barrier that confines the dog to one place in the car, such as the back section of an SUV, or use a safety harness that is specifically designed for car travel.

Read Full Q/A … : Bringing Your New Puppy Home

Q. Can you use Floxin Otic for ear infections on dogs?
ANSWER : A. Floxin Otic is an ear cleaning solution designed for the clearing of ear infections in people. While it may be similar to dog products used for ear infections, it is best to bring it to your vet’s attention first so he or she can compare it to dog-safe products. It may be that it is in the same concentration and can be safely used, or your vet can instead recommend a product that is in the right formulation.

If you are seeing an ear infection in your dog’s ears, your vet can provide you with a dog-safe medication to use. Ear infections are usually treated over a period of ten days and involve cleaning the ear 2x daily and then placing the otic ointment in the ear to stay in place until the next cleaning.